Pharmacology Mnemonics

  

 
· Cardioselective betablockers are: 

"Betablockers Acting Exclusively At Myocardium" 

Betaxolol
Acebutelol
Esmolol
Atenolol
Metoprolol

Beta-blocker main contraindications / cautions

ABCDE:

* Asthma
* Block (heart block)
* COPD
* Diabetes mellitus
* Electrolyte (hyperkalemia)

B-agonist tocolytic (contraindication or warning) 

ABCDE:
Angina (Heart disease)
BP high
Chorioamnionitis
Diabetes
Excessive bleeding

 

Beta-1 vs Beta-2 receptor location
"You have 1 heart and 2 lungs":
Beta-1 are therefore primarily in the heart.
Beta-2 primarily in the lungs.

Zero Order Kinetics -

zero WATT Power

Warfarin Alcohol
Theophylline
Phenytoin

Phenytoin advrse effct.
PHENYTOIN.
Peripheral neuropathy.
Hirsutism.
Enlargement of gum(gum hypertrophy).

Nystigmus.
Yellow colouratn of skin.
Teratogenecity.
Osteomalacia.
Increasd sleep.
Neurological(ataxia,gait)

Effects of Lithium
"LITHIUM"
LI - Leukocytes Increase
T - Tremors,Thirst
H - Hypothyroidism
IU - Increase Urine
M - Mental Confusion
Muscle Twictching
Motor Incoordination

CORTICOSTERIODS

Side Effects
C-cushings syndrome
O-osteoporosis
R-retardation of growth
T-thin skin n easy brusibility
I-infections n immunosupression
C-cataract n glaucoma
O-odema
S-supression of HPA axis
T-thining n ulceration of gastric mucosa
E-Emotional disturbance
R-rise in BP
I-Increase in hair growth(hirsuitism)
O-otherz like fetal abnormalties n hypokalemia
D-diabetes mellitus precipitation
S-stria

Aspirin: side effects 

ASPIRIN  :

Asthma
Salicyalism
Peptic ulcer disease/ Phosphorylation-oxidation uncoupling/ PPH/ Platelet disaggregation/ Premature closure of PDA

Intestinal blood loss
Reye's syndrome
Idiosyncracy
Noise (tinnitus)

Drugs causing focal to massive hepatic necrosis ...

"Very Angry Hepatocytes":

Valproic acid

Acetaminophen

Halothane

 

 Alcohol withdrawal syndrome -

SATAN ID - (meaning alcohol is the ID of SATAN)

Seizures

Anxiety

Tremors

Arrythemias

NVD

 Insomnia

Delerium tremens

Symptoms Of Mania >> DIG FAST <<

D-istractability
I-nsomnia/Impulsive behaviour
G-randiosity
F-light of Ideas
A-ctivity/Agitation
S-peech(pressured)
T-houghtlessness

Adverse Effect of Cholinergic drugs:

DUM BELS

defecation

urination

myosis

bronchoconstriction

electrical changes

lacrimation

salivation

Adverse Effects of [Valproate]
"VALPROATE"
V-omiting
A-lopecia
L-iver toxicity
P-ancreatitis
R-ashes and thrombocytopenia
O-edema
A-taxia
T-remors
E-ach others metabolism increases with carbamazepin

Contraindications of ACE inhibitors..
(PARK)
(P)regnancy.
(A)llergy.
(R)enal artery stenosis.
(K) Potassium increase.. ie. Hyperkalaemia.

 angiotensin 2 receptor blocker.......'LOVE'
L-Losartan
O-Olmesartan
V-Valsartan
E-tElmesartan

Cytochrome p450 inducers

"GPRS Cell"
Greseofulvin
...Phenytoin
Rifampicin
Smoking
Carbamezapine

  Cytochrome P450 Inhibitors

"Vitamin K Cannot Cause Enzyme Inhibition in Old Men"
Vitamin - valproate
...K -ketoconazole
Cannot -cimetidine
Cause - ciprofloxacin
Enzyme- erythromycin
Inhibition - isoniazid
in
Old - omeprazole
Men - metronidazole

Drugs for treatment of Alziemer’s disease:

River main takrain marnay aur galian denay say Ali Azmat thek o gya

River   : Rivastigmine

Main    : Mamantin

Takrain : tacrine

Galian  : galantamine

Denay   : donepazil

Ali Azmat : Alziemer’s disease

Morphine Therpeutic Uses

me gc ca hero hu

m miosis

e emisis

g git nausea vomiting constipation

c cough reflx spression

c cvs bradycardia n hypotnsion

a analgesia

h histamin release

e euphoria

r respiratory depression

o o to remember that 4 mOrphin

h hormone release effct

u uterine smooth muscl delay 2nd stage of labour

 Carbamazepine Therpeutic Uses

CBZ

Cranial nerve neuralgia

Bipolar disorder

Zeisures !

Carbamazepine Adverse Effects

OATMEAL

Osteomalacia

Aplastic anemia

Teratogenicity

Megaloblastic anemia

Exfoliative dermatitis

ADH hypersecretion

Lethargy (CNS depression)

Colchicine Adverse Effects

CHAMP

Colchicine

Hematuria

Alopecia

Myelosuppression

P eripheral neuropathy

Related to classification

TCAs are made by DAD INC

D Doxepin

A Amitriptyline

D Despramine

I Imipramine

N Nortriptyline

C Clomipramine

 Parkinsonian drugs

SALAD

S- Selegiline

A- Anti-cholinergics

L- L-dopa (with carbidopa)

A- Amantadine

D- Dopamine post-synaptic agonists (bromocriptine, pergolide, lisuride)

the PPIs

OLPER(milk )

Omeprazole

Lansoprazole

Pantoprazole

Rabeprazole

Esomeprazole

Gen anesthetics

SHINED

Sevoflurane

Halothane

isoflurane

NO

Enflurane

Desflurane

K sparing diuretscs

EAST

Epleranone

Amiloride

Spironolactone

Triameterene

Which drug(s) cause this reaction: Agranulocytosis?
-Cloazapine -carbamazapine -colchicine-PTU

Which drug(s) cause this reaction: Aplastic anemia?
-Chloramphenicol -benzene -NSAIDS -PTU -phenytoin
...
Which drug(s) cause this reaction: Cardiac toxicity?
-Daunorubicin &Doxorubicin

Which drug(s) cause this reaction: Cinchonism (2)?
-Quinidine -quinine

Which drug(s) cause this reaction: Cutaneous flushing (4)?
-Niacin -Ca++ channel blockers -adenosine -vancomycin

Which drug(s) cause this reaction: Focal to massive hepatic necrosis (4)?
-Halothane -Valproic acid-acetaminophen

Which drug(s) cause this reaction: G6PD hemolysis (8)?
-Sulfonamides -INH- Ibuprofen -primaquine - nitrofurantoin /-pyrimethamine -
chloramphenicol

Which drug(s) cause this reaction: Gingival hyperplasia?
-Phenytoin

Which drug(s) cause this reaction: Gray baby syndrome?
-Chloramphenicol

Which drug(s) cause this reaction: Gynecomastia (6)?
-Cimetidine -ketoconazole-spironolactone -digitalis-EtOH -estrogens

Which drug(s) cause this reaction: Hepatitis?
-Isoniazid

Which drug(s) cause this reaction: Hot flashes?
-Tamoxifen

Which drug(s) cause this reaction: Neuro and Nephrotoxic?
-polymyxins

Which drug(s) cause this reaction: Osteoporosis (2)?
-Corticosteroids -heparin

Which drug(s) cause thisreaction: Oto and Nephrotoxicity (3)?
-aminoglycosides -loop diuretics -cisplatin

Which drug(s) cause this reaction: P450 induction(6)?
-Barbiturates -phenytoin -carbamazipine -rifampin -griseofulvin -quinidine

Which drug(s) cause this reaction: P450 inhibition(6)?
-Cimetidine -ketoconazole-grapefruit juice -erythromycin -INH -sulfonamides

Which drug(s) cause this reaction: Photosensitivity (3)?
-Tetracycline -amiodarone -sulfonamides

Which drug(s) cause this reaction: Pseudomembranous colitis?
-Clindamycin

Which drug(s) cause this reaction: Pulmonary fibrosis(3)?
-Bleomycin -amiodarone -busulfan

Which drug(s) cause this reaction: SLE-like syndrome
-Hydralazine -Procainamide -INH -phenytoin

Which drug(s) cause this reaction: Stevens-Johnsonsyn. (3) ?
-Ethosuxamide -sulfonamides -lamotrigine

Which drug(s) cause this reaction: Tardive dyskinesia?
-Antipsychotics

Which drug(s) cause this reaction: Tendonitis and rupture?
-Fluoroquinolones

Which drug(s) cause this reaction: Thrombotic complications?
-Oral Contraceptives

Which drug(s) cause this reaction: Torsade de pointes (2) ?
-Class III antiarrhythmics (sotalol) -class IA (quinidine)

Which drug(s) cause this reaction: Tubulointerstitial Nephritis (5)?
-Sulfonamides -furosemide -methicillin -rifampin -NSAIDS

Which drug(s) cause this reaction: Disulfram-like reaction (4) ?
-Metronidazole -certain cephalosporins -procarbazine -sulfonylureas

Which drug(s) cause this reaction: Drug induced Parkinson's (4) ?
-Haloperidol -chlorpromazine -reserpine

Which drug(s) cause this reaction: Extrapyramidal side effects (3)?
-Chlorpromazine -thioridazine -haloperidol

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